Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model

نویسندگان

  • Mu Yang
  • Jian-Xin Dong
  • Lu-Bin Li
  • Hai-Jie Che
  • Jun Yong
  • Fu-Bo Song
  • Tao Wang
  • Jv-Wen Zhang
چکیده

Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postconditioning (LIPo) and remote ischemia postconditioning (RIPo) on intestinal I/R injury. We concluded that LIPo affords protection in intestinal I/R injury in a comparable fashion with RIPo by decreasing oxidative stress, neutrophil activation, and apoptosis.

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عنوان ژورنال:

دوره 2016  شماره 

صفحات  -

تاریخ انتشار 2016